CANDLE - A Study of Acute Health Effects of Exposure to Particles Generated by Candles

Summary

INTRODUCTION: Particle contamination is suggested to have substantial negative effects on health, with candles emitting huge amount of particles, thus being one of the largest contributors to indoor air pollution. Chronic low levels of exposure to indoor particles over time is an important risk factor for the health of the population as a whole and it becomes particularly important for vulnerable groups like people suffering from respiratory diseases such as asthma.

AIM: In a randomized controlled cross-over trial the difference in health effects between two candles I) a standard candle and II) a low emission candle modified from the standard candle is studied.

Conditions

• Inflammatory Response
• Symptoms and Signs

Interventions

OTHER

Candle C

Burning candles will produce particulate air pollution being passed on an exposure chamber where the participants will be sitting for 5 hours.

OTHER

Candle 1

Burning candles will produce particulate air pollution being passed on an exposure chamber where the participants will be sitting for 5 hours.

Sponsors & Collaborators

• Lund University

  collaborator OTHER

• University of Copenhagen

  collaborator OTHER

• Danish Technological Institute

  collaborator UNKNOWN

• ASP-HOLMBLAD A/S

  collaborator UNKNOWN

• COOP Denmark

  collaborator UNKNOWN

• Danwax

  collaborator UNKNOWN

• Liljeholmens Stearinfabrik

  collaborator UNKNOWN

• Promol

  collaborator UNKNOWN

• European Candle Association

  collaborator UNKNOWN

• University of Aarhus

  lead OTHER

Principal Investigators

• Torben Sigsgaard, Prof. · University of Aarhus

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Max Age

25 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2020-09-01

Primary Completion

2020-12-31

Completion

2020-12-31

Countries

• Denmark

Study Locations