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A Study to Compare the Effects of Different Sized Particles on Cells in the Nose

NCT01257191 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 25

Last updated 2017-01-11

No results posted yet for this study

Summary

The goal of this study is to see how the type and size of particles found in air pollution affects inflammation in the nose in people who are skin test positive to at least one allergen. It has been observed that pollution makes allergies worse. It has also been suggested that very small particles may affect allergies more than larger particles.

Conditions

  • Hypersensitivity, Immediate
  • Atopic Hypersensitivity

Interventions

DRUG

Carbon Black

source: commercial

DRUG

Diesel Exhaust Particles

source: diesel engine

DRUG

Fine Concentrated Ambient Particles

source: concentrated ambient air

DRUG

Ultrafine Concentrated Ambient Particles

source: concentrated ambient air

DRUG

Saline

Saline solution

Sponsors & Collaborators

Principal Investigators

  • Maria G Lloret, MD · University of California, Los Angeles

Study Design

Allocation
RANDOMIZED
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-04-30
Primary Completion
2012-01-31
Completion
2012-01-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01257191 on ClinicalTrials.gov