Metabolic and Therapeutic Effects of American and Korean Red Ginseng in the Treatment of Type 2 Diabetes

Summary

The study is a 2 phase double blind randomized placebo control trial. The objective is to asses the metabolic and therapeutic effects of American Ginseng (Panax quinquefolius L.) extract and Korean Red Ginseng (steamed Panax C.A. Meyer) extract in the management of type 2 diabetes in a 12 week period. One Hundred and twenty subjects with type 2 diabetes (hyperglycemia key inclusion criteria: HbAlc≥6.5% - ≤ 8.1% ) will participate in the study (36 men and 36 post-menopausal women).

Conditions

• Diabetes Mellitus Type 2

Interventions

DIETARY_SUPPLEMENT

American Ginseng (Panax quinquefolius L.) and Korean Red Ginseng (steamed Panax C.A. Meyer)

1.5 grams American Ginseng and 1.5 grams Korean Red Ginseng are to be taken in capsulated form. Two capsules are taken with every meal, for a total of 6 capsules per day for 12 weeks

DIETARY_SUPPLEMENT

American Ginseng (Panax quinquefolius L.)

3 grams of American Ginseng is to be taken in capsulated form. Two capsules are taken with every meal, for a total of 6 capsules per day for 12 weeks

DIETARY_SUPPLEMENT

Wheat Bran

3 grams of Wheat Bran is to be taken in capsulated form. Two capsules are taken with every meal, for a total of 6 capsules per day for 12 weeks

Sponsors & Collaborators

• Canadian Diabetes Association

  collaborator OTHER

• Unity Health Toronto

  lead OTHER

Principal Investigators

• Vladimir Vuksan, PhD · Clinical Nutritian and Risk Factor Modification Centre

• Alexandra Jenkins, PhD · Clinical Nutrition and Risk Factor Modificatrion Centre

• Lawerence Leiter, MD · St. Michaels Hospital

• Leanne De Souza, M.Sc. · Clinical Nutrition and Risk Factor Modificatrion Centre

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

40 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2008-09-30

Primary Completion

2015-08-31

Completion

2015-08-31

Countries

• Canada

Study Locations