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Anti-diabetic Effect of Gynostemma Pentaphyllum Tea in Type 2 Diabetic Patients

NCT00786500 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2010-12-06

No results posted yet for this study

Summary

The aim of the present study was to investigate the long-term effects on blood glucose concentrations and possible adverse effects of an extract of Gynostemma pentaphyllum (GP). This is a plant growing in the mountain regions of Northern Vietnam and previously being used in traditional medicine. The GP extract, or placebo, was randomized to newly diagnosed patients with type 2 diabetes and administered as a "tea", 3 g two times daily during 12 weeks. All patients received instructions regarding diet and physical exercise. Oral glucose tolerance tests were performed at baseline and then every 4 weeks, and blood tests were taken with the purpose to monitor lipids, kidney and liver function, body weight and blood pressure.

Conditions

Interventions

DIETARY_SUPPLEMENT

Gynostemma pentaphyllum tea

3 grams twice daily, orally

DIETARY_SUPPLEMENT

Placebo tea

3 grams twice daily, orally

Sponsors & Collaborators

  • Karolinska Institutet

    collaborator OTHER

  • Swedish International Development Cooperation Agency (SIDA)

    collaborator OTHER_GOV

  • Hanoi Medical University

    lead OTHER

Principal Investigators

  • Claes Goran Ostenson, MD, PhD · Karolinska Institutet

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-02-28
Primary Completion
2007-09-30
Completion
2007-12-31

Countries

  • Vietnam

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00786500 on ClinicalTrials.gov