Impact of Trans Fatty Acids From Natural and Industrial Origin in the Induction of Insulin Resistance Development
NCT00617435 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 66
Last updated 2025-11-24
Summary
The investigators' project has as for principal objective to understand the impact of trans fatty acids from dairy products and industrial origin on the development of insulin resistance in obese woman. Because of the different isomeric position of the double bound those trans fatty acids may have different metabolic effects.
Conditions
Interventions
- DIETARY_SUPPLEMENT
-
vaccenic acid enriched diet
The experimental milk fat, entitled "vaccenic acid enriched milk fat" (VAMF), has been obtained by feeding cows with a diet containing sunflower oil.
- DIETARY_SUPPLEMENT
-
Elaidic acid enriched diet
Mixture of vegetable oils (including partially hydrogenated oils)
- DIETARY_SUPPLEMENT
-
control diet
Mixed of different oil
Sponsors & Collaborators
-
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
lead OTHER
Principal Investigators
-
Yves Boirie, MD, PU-PH · UMR1019 INRA - Université Clermont1
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 50 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2007-10-31
- Primary Completion
- 2007-12-31
- Completion
- 2009-01-31
Countries
- France
Study Locations
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