MedTrace Logo

Periodontal and Periapical Inflammation and Pregnancy

NCT00490165 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2012-04-06

No results posted yet for this study

Summary

This is a retrospective chart review of patient records at the University of Mississippi Medical Center. We are not actively recruiting patients for this study. Recent animal studies we conducted showed that periapical abscesses during pregnancy cause a systemic inflammatory response in the mother. Also due to the increase in TNF-alpha (an inflammatory cytokine) the mother also become insulin resistant and thus developed gestational diabetes. Periodontal inflammation has been shown in the research to lead to low-birth weight and pre-term birth. We are looking retrospectively to see if an association exists in charted data between periapical and periodontal inflammation and adverse pregnancy outcomes.

Conditions

Sponsors & Collaborators

  • Roger Johnson

    lead OTHER

Principal Investigators

  • Jennifer L Bain, BS · University of Mississippi Medical Center

  • Roger Johnson, PhD; DMD · University of Mississippi Medical Center

Eligibility

Min Age
10 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-03-31
Primary Completion
2011-12-31
Completion
2011-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00490165 on ClinicalTrials.gov