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Association of Periodontal Inflammation on Immune Response in Wound Healing

NCT04805320 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 25

Last updated 2025-12-10

No results posted yet for this study

Summary

Subjects who are in need of extraction of a posterior tooth will be recruited for this study. Prior to extraction, periodontal clinical markers of inflammation, body-mass index and dental radiographs will be measured/taken. The posterior tooth will be atraumatically extracted and a small soft tissue biopsy of the extraction site will be taken. At the two week follow-up, sutures will be removed and another small biopsy of soft tissue will be taken. Subjects will be seen again at 3 months for a final collection of clinical data and radiographs.

Conditions

  • Inflammation of Mouth

Interventions

PROCEDURE

Dental Extraction

Extraction

Sponsors & Collaborators

  • University of Nebraska

    lead OTHER

Principal Investigators

  • Joseph B Bavitz, DMD · University of Nebraska, College of Dentistry

Eligibility

Min Age
21 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-09-01
Primary Completion
2026-06-30
Completion
2026-07-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04805320 on ClinicalTrials.gov