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Apical Periodontitis and Mental Health

NCT06589076 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2026-04-13

No results posted yet for this study

Summary

This study is investigating the relationship between anxiety, depression and apical periodontitis (AP), a common oral inflammatory condition. The research is being conducted at the Unit of Endodontic and Conservative Dentistry, University of Siena, Italy, with participants aged over 18. Participants are divided into two groups: those with apical periodontitis and those without. The study aims to determine whether there is an association between anxiety, depression (assessed using the Hamilton Anxiety/Depression Rating Scale), and the presence or severity of apical periodontitis. Data collection includes dental exams, radiographs, and anxiety and depression assessments. This research may help to better understand how mental health and dental health are connected.

Conditions

Interventions

DIAGNOSTIC_TEST

Clinical and Radiographic assessment + Questionnaires

* Clinical and radiographic examination to assess oral health and apical periodontitis. * Questionnaires to assess Anxiety and depression.

Sponsors & Collaborators

  • University of Siena

    lead OTHER

Principal Investigators

  • Simone Grandini, PhD, DDS · University of Siena

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-01
Primary Completion
2023-04-30
Completion
2024-04-30

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06589076 on ClinicalTrials.gov