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Association of Apical Periodontitis With Systemic Level of Inflammatory Markers : A Longitudinal Intervention Study

NCT05814965 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 280

Last updated 2023-04-18

No results posted yet for this study

Summary

While cross-sectional studies have reported a significant association between diabetes and Apical Periodontics, prospective studies are scarce. This will be the first prospective interventional study to explore the cause-and-effect relation between AP and diabetes by assessment of levels of inflammatory markers in a longitudinal setting. Periapical healing in diabetics and nondiabetics will be compared after root canal treatment to evaluate the role of various physical and metabolic attributes on endodontic outcomes.

Conditions

  • Diabetes Mellitus, Type 2
  • Apical Periodontitis

Interventions

PROCEDURE

endodontic treatment in the form of root canal treatment

Patients will receive endodontic treatment, and inflammatory markers will be assessed

PROCEDURE

endodontic treatment

Patients will receive endodontic treatment in the form of root canal treatment, and inflammatory markers will be assessed along with metabolic markers assessment

DIAGNOSTIC_TEST

assessment of inflammatory marker

assessment of inflammatory markers

DIAGNOSTIC_TEST

inflammatory markers will be assessed along with metabolic markers assessment

inflammatory markers will be assessed along with metabolic markers assessment

Sponsors & Collaborators

  • Postgraduate Institute of Dental Sciences Rohtak

    lead OTHER

Principal Investigators

  • SANJAY TEWARI · POST GRADUATE INSTITUTE OF DENTAL SCIENCES,ROHTAK

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-04-05
Primary Completion
2024-12-31
Completion
2025-12-31

Countries

  • India

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05814965 on ClinicalTrials.gov