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Effects of Magnesium and Spinning Training on Echocardiographic, Inflammatory, and Aerobic Outcomes

NCT07662954 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2026-06-23

No results posted yet for this study

Summary

Regular aerobic exercise may improve cardiorespiratory fitness while modulating systemic inflammation and oxidative stress. Spinning, as a structured indoor cycling modality, provides a practical aerobic exercise model with adjustable intensity and duration, but its effects on redox balance, inflammatory status, aerobic capacity, and cardiac functional parameters may vary according to individual recovery and nutritional status. Magnesium is an essential micronutrient involved in energy metabolism, muscle contraction-relaxation, ion regulation, and inflammatory and oxidative pathways; therefore, magnesium use may be relevant to exercise adaptation and recovery.

This study aims to evaluate the associations of magnesium use and spinning training with oxidative stress, inflammation, aerobic capacity, and cardiac parameters. In this context, biochemical markers related to oxidative/antioxidant status and inflammation, aerobic performance indicators, and echocardiographic cardiac function parameters will be assessed together. The study is expected to provide real-world evidence on whether magnesium use in individuals participating in spinning training is associated with more favorable redox, inflammatory, aerobic, and cardiac profiles.

Conditions

  • Oxidative Stress
  • Inflammation
  • Physical Fitness
  • Echocardiography
  • Exercise
  • Healthy Volunteers

Interventions

BEHAVIORAL

Spinning Training

Participants will participate in a structured spinning training program during the study period. The program will consist of supervised indoor cycling sessions performed at a planned frequency, duration, and intensity.

DIETARY_SUPPLEMENT

Magnesium Supplementation

Participants will receive oral magnesium supplementation during the study period in addition to the structured spinning training program.

Sponsors & Collaborators

  • Karamanoğlu Mehmetbey University

    lead OTHER

Principal Investigators

  • Şemsi Gül Yılmaz Kocaman, PhD · Karamanoğlu Mehmetbey University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-06-01
Primary Completion
2026-08-15
Completion
2026-08-20

Countries

  • Turkey (Türkiye)

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07662954 on ClinicalTrials.gov