Acute Exercise and Microvascular Function
NCT02727439 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2016-04-04
Summary
It is well recognized that chronic exercise protects against the development of cardiovascular diseases. However, the responses of vasculature to acute exercise (AE) are not well known and not consistent in literature. Acute exertional exercise can induce large, transient increases in arterial pressure and development of metabolic acidosis which can be associated with pro-inflammatory response involving oxidant stress and circulating cytokines known to impair endothelial function.
The aim of this study is to test the impact of a single exposure to exhausting training on microvascular reactivity in healthy sedentary subjects and athletes.
Conditions
- Physical Exertion
Interventions
- OTHER
-
Acute Exhausting Exercise (AE)
A single progressive rowing training to maximal exhaustion (AE).
Sponsors & Collaborators
-
Josip Juraj Strossmayer University of Osijek
lead OTHER
Principal Investigators
-
Ines Drenjancevic, MD, PhD · Faculty of Medicine, Josip Juraj Strossmayer University of Osijek
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 30 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-02-29
- Primary Completion
- 2017-05-31
- Completion
- 2017-12-31
Countries
- Croatia
Study Locations
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