Aging, Lifestyle and Inflammation in Veterans Exercising
NCT00667030 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2026-02-20
Summary
Over half of adults in this country are overweight. This increases risk for heart and blood pressure problems, cancer, stroke and arthritis. While it is difficult to lose large amounts of weight and keep it off, even small amounts of weight loss can improve health. Furthermore, fat is increasingly recognized as a source of substances that increase inflammation. It may be that some of the adverse consequences of being overweight are due to increased inflammation. We are asking you to volunteer for a research study in which you may lose a moderate amount of weight and increase your activity. It is important that you read and understand the information on this form.
The purposes of these studies are to determine the influence(s) of age and body composition on the production of inflammatory chemicals by fat (adipose tissue), the mechanisms controlling this, and if a weight loss and aerobic exercise intervention results in a decrease in inflammation.
Conditions
- Inflammation
- Aging
- Metabolism
- Exercise
Interventions
- BEHAVIORAL
-
Weight loss and aerobic exercise training
Weight loss and aerobic exercise training
Sponsors & Collaborators
-
US Department of Veterans Affairs
collaborator FED -
University of Maryland, Baltimore
lead OTHER
Principal Investigators
-
Jacob B Blumenthal, MD · Baltimore VA Medical Center, University of Maryland
Study Design
- Allocation
- NA
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2005-07-31
- Primary Completion
- 2018-09-13
- Completion
- 2018-09-13
Countries
- United States
Study Locations
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