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Effect of Periodontal Therapy on Asprosin in Stable Angina

NCT07591844 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2026-05-18

No results posted yet for this study

Summary

This study aims to evaluate the effect of non-surgical periodontal therapy on serum asprosin levels in patients with stable angina and periodontitis. Asprosin is a novel metabolic biomarker reported to have potential protective roles in cardiovascular diseases and inflammatory processes. The study also investigates the relationship between periodontal parameters and serum asprosin levels before and after periodontal therapy.

Conditions

  • Stable Angina Pectoris
  • Periodontitis

Interventions

PROCEDURE

Non-surgical periodontal therapy (scaling and root planing)

Non-surgical periodontal therapy will include full-mouth scaling and root planing performed using hand instruments and/or ultrasonic devices to remove supra- and subgingival plaque and calculus.

PROCEDURE

Non-surgical periodontal therapy (Professional dental cleaning)

Supragingival calculus and plaque removal with standardized oral hygiene instruction.

Sponsors & Collaborators

  • Ondokuz Mayıs University

    lead OTHER

Principal Investigators

  • Sena Altintas, DDS · Ondokuz Mayis University Department of Periodontology

  • Feyza Otan Ozden, Prof. · Ondokuz Mayis University Department of Periodontology

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-05-20
Primary Completion
2026-08-20
Completion
2026-10-20

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07591844 on ClinicalTrials.gov