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EVALUATION of GINGIVAL CREVICULAR FLUID and SERUM ASPROSIN LEVELS in OBESE and NORMAL-WEIGHT INDIVIDUALS with PERIODONTITIS

NCT06879951 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2025-03-17

No results posted yet for this study

Summary

Obesity and periodontitis are chronic inflammatory diseases that share common pathological mechanisms. Asprosin, a novel adipokine discovered in 2016, has not been extensively studied in relation to periodontal tissues. In our study, we investigate the levels of asprosin in both serum and gingival crevicular fluid of patients with obesity and those of normal weight who have periodontitis. Additionally, our research aims to clarify the pathophysiological mechanisms linking periodontitis and obesity by examining local and systemic levels of TNF-α, IL-6, and asprosin, alongside clinical periodontal parameters.

Conditions

Interventions

OTHER

Participants are not assigned an intervention as part of the study.

Participants are not assigned an intervention as part of the study.

Sponsors & Collaborators

  • Gazi University Scientific Research Unit

    collaborator UNKNOWN

  • Gazi University

    lead OTHER

Principal Investigators

  • Aysen Bodur, Professor · Gazi University Faculty of Dentistry Department of Periodontology

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-08-08
Primary Completion
2024-08-10
Completion
2024-08-10

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06879951 on ClinicalTrials.gov