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Periodontal Status and TMAO Levels in Peripheral Artery Disease

NCT07449546 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 61

Last updated 2026-03-04

No results posted yet for this study

Summary

This observational study aims to evaluate the association between periodontal status and trimethylamine-N-oxide (TMAO) levels in patients diagnosed with peripheral artery disease (PAD). Both serum and saliva TMAO concentrations will be measured and compared according to periodontal health, periodontitis, and edentulism status. Clinical periodontal examinations and biological sample collection will be performed. The study seeks to investigate whether oral health status is associated with systemic TMAO levels in individuals with PAD.

Conditions

  • Periodontal Diseases
  • Edentulism
  • Peripheral Arterial Disease

Sponsors & Collaborators

  • Ankara University

    lead OTHER

Principal Investigators

  • Şivge Kurgan, DDS, PhD · Ankara University, Faculty of Dentistry

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-02-15
Primary Completion
2024-01-10
Completion
2024-01-15

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07449546 on ClinicalTrials.gov