Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Peri-implantitis and Peri-implant Mucositis
NCT05906810 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90
Last updated 2025-05-21
Summary
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment on endothelial dysfunction parameters in subjects with peri-implantitis/peri-implant mucositis and without any cardiovascular disease.
Conditions
- Atherosclerosis
- Endothelial Dysfunction
- Peri-Implantitis
- Peri-implant Mucositis
Interventions
- PROCEDURE
-
Non-surgical periodontal treatment
Subgingival biofilm ultrasonic debridement
Sponsors & Collaborators
-
University of Catania
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-10-05
- Primary Completion
- 2025-11-20
- Completion
- 2025-12-20
Countries
- Italy
Study Locations
More Related Trials
-
Evaluation of Periodontal Response to Non Surgical Therapy in Pre and Post Menopausal Women With Periodontitis
NCT02718014 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Determining the Relationship Between the Atherosclerosis and Periodontopathogenic Microorganisms
NCT02977351 ·Status: COMPLETED ·Phase: NA
-
Type I Diabetes and Non-surgical Periodontal Treatment
NCT05569525 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Periodontal Therapy Effect on the Ratio of TNF-α to IL-10 in Periodontis With/Out DM
NCT06539039 ·Status: COMPLETED ·Phase: NA
-
Influence of Environmental Factors on the Efficacy of Non-surgical Periodontal Treatment. A Pre-post Quasi-experimental Study
NCT04769622 ·Status: UNKNOWN
-
Assessment of the Effect of Non-surgical Periodontal Treatment on Endothelial Function- a Prospective Study
NCT05691426 ·Status: UNKNOWN
-
Effect of Periodontal Therapy on Biomarkers in Periodontitis
NCT05005923 ·Status: COMPLETED ·Phase: NA
-
Comparative Evaluation of Minimally Invasive Nonsurgical Periodontal Therapy Versus Conventional Subgingival Instrumentation
NCT05876455 ·Status: UNKNOWN ·Phase: NA
-
Evaluation of Non - Surgical Periodontal Therapy in Diabetic Patients.
NCT03764410 ·Status: COMPLETED ·Phase: NA
-
Impact of Nonsurgical Periodontal Therapy on Oral Health Related Quality of Life
NCT06143085 ·Status: RECRUITING ·Phase: NA
-
Gut Microbial Changes After Periodontal Treatment
NCT04982302 ·Status: COMPLETED
-
Amelogenins and Systemic Inflammation After Periodontal Surgical Therapy
NCT03590093 ·Status: COMPLETED ·Phase: NA
-
Evaluation of the Systemic Burden of Non-surgical Periodontal Therapy: A Randomized Clinical Trial on Five Different Treatment Protocols
NCT07077122 ·Status: RECRUITING ·Phase: NA
-
Evaluation of The Periodontal Parameters Following Non-Surgical Periodontal Therapy With and Without Adjunctive Use of Injectable Platelet Rich Fibrin: A Randomized Controlled Clinical Trial
NCT07090265 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Effect of Internal and External Micro-needling in Treatment of Stage III Periodontitis
NCT06578403 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
The Effects of Periodontal Therapy on Glycemic Control in Diabetic Patients
NCT03783845 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Non-surgical Periodontal Therapy on Cardiovascular Risk
NCT05459727 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
The Effectiveness of Root Planing and Injectable Platelet-Rich Fibrin in Smoking Patients With Periodontitis
NCT07049549 ·Status: COMPLETED ·Phase: NA
-
Effects of Non-surgical Periodontal Therapy on Severe Periodontitis and Hyperlipidemia
NCT05548933 ·Status: UNKNOWN
-
Metabolic Effects of Treatment of Chronic Periodontitis in Non-diabetic Subjects
NCT02830113 ·Status: COMPLETED ·Phase: NA
-
Effect of Non-surgical Periodontal Treatment on HbA1c in Type 2 Diabetic Patients
NCT02652026 ·Status: COMPLETED ·Phase: NA
-
Effect of Non-surgical Periodontal Therapy in Hypertensive Patients With Assessment of Endocan and TNF-α Levels in GCF
NCT06627192 ·Status: NOT_YET_RECRUITING
-
Effect of Nonsurgical Periodontal Therapy on Salivary Biomarkers Related to Bone Turnover in Smoker and Nonsmoker Periodontitis Patients
NCT06270004 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Mechanism of Indocyanine Green-based Photodynamic Therapy for Treating Periodontitis
NCT03557827 ·Status: UNKNOWN ·Phase: PHASE3
-
Effect of Tooth Cleaning in Smokers and Non Smokers With Gum Disease.
NCT02930356 ·Status: COMPLETED ·Phase: NA