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Protein Complementation of Plant-based Diets.

NCT07151625 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2025-09-03

No results posted yet for this study

Summary

Amino acids are the building blocks of proteins which are needed by the body for growth, and bodily functions. If even one amino acid is in short supply, this will negatively affect growth and various functions in the body. Animal foods like meat, fish and chicken contain all the amino acids needed by the body in the correct proportion. These foods are considered high quality protein foods. However plant proteins like lentils, wheat, rice are low in at least one amino acid. This means that plant proteins are considered low quality proteins.

Data from the investigators lab and others show that when eating plant foods, combining grains and legumes like rice and beans, peanut butter and bread, (protein complementation) will provide a complete protein which contains all the amino acids needed by the body. However, some maintain that it is not necessary to combine foods like grains and legumes in the same meal as long as all the amino acids are consumed within a 24h period. This has never been tested.

The goal of this study is to compare the effects non-complementation to protein complementization on whole body protein metabolism in young and older adults.

Conditions

  • Each Participant Will be Studied Over 5 Dietary Periods, Each Over 9d

Interventions

OTHER

Diet, whole food provided to participants over 5 x 9 day period

5 diets provided to participants over 9 days each and whole body protein synthesis, protein breakdown and protein balance assessed after each period.

OTHER

Diet

5 different diet types

Sponsors & Collaborators

  • The Hospital for Sick Children

    lead OTHER

Principal Investigators

  • Glenda Courtney-Martin, PhD, RD · Research Institute, The Hospital for Sick Children

Study Design

Allocation
NA
Purpose
OTHER
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
79 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-10-01
Primary Completion
2029-09-30
Completion
2029-09-30

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07151625 on ClinicalTrials.gov