The Effectiveness of a Diet With Beef as Key Protein Component Versus a Plant-Based Diet to Support Integrated Muscle Protein Synthesis Rates in Healthy Older Individuals
NCT07049224 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32
Last updated 2025-07-03
Summary
Muscles are composed out of proteins. These proteins in turn are composed out of smaller building blocks, called amino acids. By consuming a sufficient amount of dietary protein, a sufficient amount of amino acids become available to build new muscle proteins. The body's ability to build these new muscle proteins is of great importance to maintain muscle strength and function.
Previous research suggests that a meal containing proteins from meat results in a better stimulation of the body's ability to build muscle proteins, when compared to a meal containing only plant-based proteins. However, these previous studies have only been performed following the ingestion of a single meal. As a result it is currently unknown how the muscles respond to a more prolonged ingestion of a diet containing animal/meat products, in comparison to a plant-based diet. Therefore, this study aims to investigate how fast new muscle proteins are being build when consuming a diet containing animal/meat products, in comparison to a plant-based (vegan) diet.
Conditions
- Muscle Protein Synthetic Response to Protein
Interventions
- OTHER
-
Meat diet
Participants will be subjected to a 10-day diet containing meat and animal products. During the interventional period participants will perform unilateral lower limb resistance exercise.
- OTHER
-
Plant diet
Participants will be subjected to a 10-day diet containing plant products. During the interventional period participants will perform unilateral lower limb resistance exercise.
Sponsors & Collaborators
-
National Cattlemen's Beef Association
collaborator INDUSTRY -
Maastricht University Medical Center
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 65 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-12-09
- Primary Completion
- 2026-04-30
- Completion
- 2026-04-30
Countries
- Netherlands
Study Locations
More Related Trials
-
Combined Nutrient Intake and Muscle Protein Synthesis
NCT01239277 ·Status: COMPLETED ·Phase: NA
-
Nutrient Synergy in Beef and Stimulation of Protein Synthesis in Elderly
NCT01415973 ·Status: COMPLETED ·Phase: NA
-
The Anabolic Properties of Fortified Plant-based Protein in Older People
NCT05711095 ·Status: COMPLETED ·Phase: NA
-
Effects of Beef Protein Consumption on Energy Intake
NCT01646749 ·Status: COMPLETED ·Phase: NA
-
Postprandial Amino Acid Response After Protein Consumption
NCT04935788 ·Status: UNKNOWN ·Phase: NA
-
Mycoprotein as the Basis of a Sustainable Diet to Support Muscle Mass Maintenance and Reconditioning in Older Adults.
NCT04325178 ·Status: COMPLETED ·Phase: NA
-
Leucine Co-ingestion and Myofibrillar Protein Synthesis in Older Adults
NCT02371278 ·Status: COMPLETED ·Phase: NA
-
The Impact of Beef on Muscle Fatigue in Older Adults
NCT05860088 ·Status: COMPLETED ·Phase: NA
-
Post-exercise Recovery After Dietary Protein Ingestion in Healthy Young Men (Meat-Milk Study)
NCT01578590 ·Status: COMPLETED ·Phase: NA
-
Nutritional and Physical Intervention During Bed Rest
NCT07280819 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effect of Incorporating Lean Beef Into a Protein-rich Diet During Resistance Training on Muscle and Tendon Strength in Older Women
NCT04347447 ·Status: UNKNOWN ·Phase: NA
-
The Impact of Plant-based Blends on Skeletal Muscle Protein Synthesis Rates in Older Adults
NCT05917223 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Assessing the Impact of a Leucine Enriched Whey Protein vs Isonitrogenous Whey on Muscle Protein Synthetic Responses in the Rested and Acute Post Exercise States in Older Adults
NCT06971822 ·Status: RECRUITING ·Phase: NA
-
Effects of Whey and Collagen Protein Blend on Protein Synthesis Rates
NCT05386771 ·Status: COMPLETED ·Phase: NA
-
The Effects of Resistance Training and Protein Supplementation in Healthy Elderly Men and Women.
NCT01004588 ·Status: COMPLETED ·Phase: NA
-
Effects of Protein Supplementation on Brain Function
NCT07057245 ·Status: RECRUITING ·Phase: NA
-
Supplementation of a Leucine-enriched Protein Blend
NCT03796897 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Plant Protein Blend and Milk Protein Supplements in Older Individuals
NCT06403137 ·Status: COMPLETED ·Phase: NA
-
Diet and Muscle Function In Older Adults
NCT02069314 ·Status: COMPLETED ·Phase: NA
-
Protein Intake and Exercise-induced Muscle Damage
NCT06235476 ·Status: COMPLETED ·Phase: NA
-
Effect of Nutrition on Muscle Protein Synthesis
NCT00604929 ·Status: COMPLETED ·Phase: NA
-
Effects of Beef Consumption on Skeletal Muscle Protein Homeostasis and Inflammatory Factors in Pre- and Postmenopausal Females
NCT05714462 ·Status: COMPLETED ·Phase: NA
-
Effect of Supplementing a Mixed Macronutrient Beverage With Graded Doses of Leucine on Myofibrillar Protein Synthesis
NCT01885429 ·Status: COMPLETED ·Phase: NA
-
Postprandial Muscle Protein Synthesis Following Wheat Protein Ingestion in Vivo in Humans
NCT01952639 ·Status: COMPLETED ·Phase: NA
-
Protein Supply in Elderly
NCT01317511 ·Status: COMPLETED ·Phase: NA