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A Meal-based Comparison of Protein Quality, Complementary Proteins and Muscle Anabolism

NCT03816579 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 23

Last updated 2021-04-29

No results posted yet for this study

Summary

To highlight the importance of protein quality rather than the total protein content of a meal, the investigators will demonstrate that unlike high quality proteins, a single meal containing 30 g of an incomplete protein source does not stimulate skeletal muscle protein synthesis. Secondly, the investigators will directly challenge a prevalent, but untested, assertion that has the potential to negatively impact health. The goal is to demonstrate that complementary plant-proteins (i.e., two or more incomplete protein sources) must be consumed at the same meal to stimulate protein synthesis.

Conditions

  • Protein
  • Diet
  • Skeletal Muscle

Interventions

OTHER

PRO-A

30 g of beef protein will be consumed at each meal

OTHER

PRO-B

30 g of complementary proteins will be consumed at each meal

OTHER

PRO-C

30 g of complementary proteins will be consumed over 24 hours

Sponsors & Collaborators

  • The University of Texas Medical Branch, Galveston

    lead OTHER

Principal Investigators

  • Doug Paddon-Jones, PhD · University of Texas

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
45 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-03-26
Primary Completion
2021-01-21
Completion
2021-01-21

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03816579 on ClinicalTrials.gov