Role of Aging and Individual Variation in Exercise Training Responsiveness
NCT06471569 · Status: SUSPENDED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 26
Last updated 2026-05-22
Summary
The primary purpose of this study is to assess the effects of aging on markers of physical reserve and exercise-induced adaptations in resilience in older adults who completed a structured exercise program within the last 15 years (Parent trial: STRRIDE-PD; NCT00962962). This feasibility pilot study will enroll up to 26 participants to complete a 6-month aerobic exercise intervention.
Conditions
- Prediabetic State
- Cardiovascular Diseases
- Insulin Resistance
- Obesity
Interventions
- BEHAVIORAL
-
Low/Mod
Aerobic exercise at 50% peak oxygen consumption for the number of weekly minutes prescribed in the original STRRIDE trial
- BEHAVIORAL
-
High/Mod
Aerobic exercise at 50% peak oxygen consumption for the number of weekly minutes prescribed in the original STRRIDE trial
- BEHAVIORAL
-
High/Vig
Aerobic exercise at 75% peak oxygen consumption for the number of weekly minutes prescribed in the original STRRIDE trial
Sponsors & Collaborators
-
National Institutes of Health (NIH)
collaborator NIH -
National Institute on Aging (NIA)
collaborator NIH - lead OTHER
Principal Investigators
-
Leanna M Ross, PhD · Duke University
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 60 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-04-02
- Primary Completion
- 2026-09-30
- Completion
- 2026-09-30
Countries
- United States
Study Locations
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