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Effect of Protein and Retinol on Alcohol-induced FGF21

NCT06105476 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 31

Last updated 2024-08-27

No results posted yet for this study

Summary

The aims of this study are two-fold. First to investigate the influence of protein on the FGF21 response induced by alcohol, and second to investigate the influence of retinol on FGF21 concentrations and the FGF21 response induced by alcohol. Exploratory, and in order to investigate mechanisms behind the potential influence on alcohol-induced FGF21 response from protein or retinol intake, plasma glucose, insulin, glucagon, ethanol, acetaldehyde, acetate, retinol, retinoic acid, as well as subjective rating of appetite, will be measured.

Conditions

  • Healthy

Interventions

OTHER

Alcohol

Test drink with 12 g alcohol (30 g vodka 40%) in water

OTHER

Alcohol+protein

Test drink with 12 g alcohol (30 g vodka 40%) and 25 g whey protein in water

OTHER

Alcohol+retinol

Test drink with 12 g alcohol (30 g vodka 40%) and 1000 μg retinol in water

OTHER

Retinol

Test drink with 1000 μg retinol in water

Sponsors & Collaborators

  • University of Copenhagen

    lead OTHER

Principal Investigators

  • Niels Grarup · Novo Nordisk Foundation Center for Basic Metabolic Research, Health and Medical Sciences, University of Copenhagen

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-11-20
Primary Completion
2024-03-31
Completion
2024-03-31

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06105476 on ClinicalTrials.gov