Automated Imaging Differentiation of Parkinsonism

Summary

The purpose of this study is to test the performance of the AID-P across 21 sites in the Parkinson Study Group. Each site will perform imaging, clinical scales, diagnosis, and will upload the data to the web-based software tool. The clinical diagnosis will be blinded to the diagnostic algorithm and the imaging diagnosis will be compared to the movement disorders trained neurologist diagnosis.

Conditions

• Parkinson Disease
• Multiple System Atrophy, Parkinson Variant
• Progressive Supranuclear Palsy

Interventions

DIAGNOSTIC_TEST

AIDP

Machine learning algorithm of imaging data

Sponsors & Collaborators

• Augusta University

  collaborator OTHER

• Albany Medical College

  collaborator OTHER

• Beth Israel Deaconess Medical Center

  collaborator OTHER

• Duke University

  collaborator OTHER

• Johns Hopkins University

  collaborator OTHER

• Massachusetts General Hospital

  collaborator OTHER

• Northwestern University

  collaborator OTHER

• Ottawa Hospital Research Institute

  collaborator OTHER

• Penn State University

  collaborator OTHER

• University of Alabama at Birmingham

  collaborator OTHER

• University of California, San Diego

  collaborator OTHER

• University of California, San Francisco

  collaborator OTHER

• University of Chicago

  collaborator OTHER

• University of Michigan

  collaborator OTHER

• University of Minnesota

  collaborator OTHER

• University of South Florida

  collaborator OTHER

• Centre for Addiction and Mental Health

  collaborator OTHER

• Wake Forest University

  collaborator OTHER

• Washington University School of Medicine

  collaborator OTHER

• University of Kentucky

  collaborator OTHER

• National Institute of Neurological Disorders and Stroke (NINDS)

  collaborator NIH

• University of Florida

  lead OTHER

Eligibility

Min Age

40 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2021-07-22

Primary Completion

2026-03-31

Completion

2026-03-31

Countries

• United States
• Canada

Study Locations