Digital Diagnostics and Intervention Services for Parkinson's Disease

Summary

People with Parkinson's have infrequent clinical consultation (once every 12-18 months) and limited rehabilitation.

Assessment play an important role in these consultations to help clinicians understand patients' health status and disease progression necessary to adjust treatment plans. The current way of measuring is the UPDRS which needs a clinician to do this and takes 30 minutes. There is a strong need for more frequent and accurate Parkinson's assessments in the clinic and at home to detect changes early and then give appropriate support and drug and physiotherapy quickly. There is a need to develop good home digital physiotherapy tools to increase the amount of therapy. Here the investigators are testing new digital technologies to do these assessments in the home and clinic and a new digital physiotherapy device in the home. The investigators aim to conduct a clinical study with 50 people with Parkinson's (50 from UK) with the UPDRS, (a rating scale that is commonly used in clinical settings to evaluate the progression of Parkinson's disease) and 30 healthy adults. The investigators will develop and investigate if two new digital devices, one the MachineMD that measures eye movement and one the gaitQ that measures gait can be used instead of the MDS-UPDRS (motor) using digital gait and ophthalmic features in the clinic setting. The investigators will investigate the effect of a physiotherapy gait intervention gaitQ Tempo in the home context for two weeks and of doing the gait measure at home. The investigators will determine the potential of the gaitQ intervention to improve key gait metrics in order to collect clinical evidence and of using the gaitQ as a cuing system over a 2-week period on gait and other movement measures in the home and community

Conditions

• Brain Diseases
• Central Nervous System Diseases
• Nervous System Diseases
• Joint Diseases
• Musculoskeletal Diseases
• Parkinson Disease
• Basal Ganglia Diseases
• Movement Disorders
• Synucleinopathies
• Neuro-Degenerative Disease
• Demyelinating Disease, Autoimmune, CNS
• Demyelinating Disease
• Autoimmune Diseases
• Immune System Diseases
• Bone Diseases, Metabolic
• Bone Diseases
• Arthritis
• Osteoporosis
• Multiple Sclerosis

Sponsors & Collaborators

• GaitQ company

  collaborator UNKNOWN

• University of Exeter

  lead OTHER

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2024-10-15

Primary Completion

2025-07-31

Completion

2026-03-01