MedTrace Logo

An Evaluation of Salivary Oxidant and Antioxidant Levels in Peri-implant Health and Disease

NCT05724706 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 88

Last updated 2023-02-13

No results posted yet for this study

Summary

Objectives: Inflammatory lesions develop in the tissues surrounding implants are referred to as peri-implant diseases. Oxidants, play a role in inflammatory lesions. The study aimed to determine oxidant and antioxidant levels in the saliva of patients with various levels of peri-implant diseases and the relationship between oxidative stress and peri-implant diseases.

Material and methods: Sixty-seven patients with at least one dental implant applied in our clinic were included in the study. The patients were divided into 3 groups; with peri-implantitis (PI), with marginal bone loss (MBL) and with healthy peri-implant (HI) tissues. Twenty-one individuals who didn't have any dental implants were included the study as a healthy control group (HC). For oxidant concentration, total oxidant status (TOS), advanced oxidation protein products (AOPP), and for antioxidant concentration, total antioxidant status (TAS), were investigated.

Conditions

  • Peri-Implantitis
  • Bone Loss in Jaw
  • Dental Implant Failed
  • Dental Implant Failure Nos
  • Oxidative Stress

Sponsors & Collaborators

  • Istanbul University

    collaborator OTHER

  • Istanbul Arel University

    collaborator OTHER

  • Biruni University

    lead OTHER

Principal Investigators

  • ZEYNEP S PEKCETIN-BAYAV, ASST. PROF. · Biruni University

Eligibility

Min Age
18 Years
Max Age
67 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-09-01
Primary Completion
2018-01-05
Completion
2018-03-13

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05724706 on ClinicalTrials.gov