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Innovative Methods to Reduce Emissions and Health Impacts of Deep-frying

NCT05278910 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2022-03-14

No results posted yet for this study

Summary

Cooking oil fume (COF) is a significant source of PM2.5 for poorly ventilated space indoors and in urban streets near restaurants or night markets. Modern Chinese cooking produces high concentration of COF especially from deep-frying foods and stirred frying. Emission from high-temperature frying has been classified by the IARC as Group 2A carcinogen. Cooks are at high risk of exposure to toxic compounds from cooking fumes. However, more of the COF-related studies focused on the home kitchen and less addresses the problems in the restaurants. Studying health hazards and biomarkers of cooks may provide opportunities to understand biological mechanisms and to search and test efficacy for measures to overturn such risks.

The investigators will recruit 80 cooks who handle deep-frying and stirred frying on daily basis. The 80 cooks will be randomized to 4 groups: (1) control, (2) vegetable and fruits extract (V\&F) group, (3) fish oil group, and (4) V\&F-fish oil group will be provided to the participants for 2 months V\&F capsules (equivalent to 4 servings a day) and fish oil capsules (1\~1.5 serving a day) and placebos of the same appearance. Heart rate variability (HRV), pulmonary functions, bio-markers, oxylipins and metabolomics profile will be measured as outcomes.

Conditions

Interventions

OTHER

Soybean oil + Roasted wheat flour

Assign soybean oil capsule and roasted wheat flour

DIETARY_SUPPLEMENT

Fish oil + Roasted wheat flour

Assign fish oil and roasted wheat flour

DIETARY_SUPPLEMENT

Soybean oil + Vegetable and fruit extracts

Assign soybean oil and vegetable and fruit extracts

DIETARY_SUPPLEMENT

Fish oil + Vegetable and fruit extracts

Assign fish oil and vegetable and fruit extracts

Sponsors & Collaborators

  • Academia Sinica, Taiwan

    lead OTHER

Principal Investigators

  • Wen-Harn Pan, PhD · Institute of Biomedical Sciences, Academia Sinica

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-03-14
Primary Completion
2024-12-31
Completion
2024-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05278910 on ClinicalTrials.gov