MedTrace Logo

Effects of Fish Oil in Alleviating Health Hazards Associated With Ozone Exposure

NCT03697499 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2020-02-05

No results posted yet for this study

Summary

This study aims to evaluate whether dietary supplementation with fish oil can protect against the cardiopulmonary effects induced by ozone exposure.

Conditions

  • Cardiovascular System
  • Respiratory System
  • Oxidative Stress
  • Inflammation

Interventions

COMBINATION_PRODUCT

fish oil and acute ozone exposure

The participants will take fish oil (2.2 g/day, two 1.1-g capsules daily) in divided doses. Two hour ozone exposure (200 ppb ozone) will be conducted in a chamber after four weeks of supplementation.

COMBINATION_PRODUCT

fish oil and sham exposure

The participants will take fish oil (2.2 g/day, two 1.1-g capsules daily) in divided doses. Two hour shame exposure (0 ppb ozone) will be conducted in a chamber after four weeks of supplementation.

COMBINATION_PRODUCT

soy oil and acute ozone exposure

The participants will take soy oil (2.2 g/day, two 1.1-g capsules daily) in divided doses. Two hour ozone exposure (200 ppb ozone) will be conducted in a chamber after four weeks of supplementation.

COMBINATION_PRODUCT

soy oil and sham exposure

The participants will take soy oil (2.2 g/day, two 1.1-g capsules daily) in divided doses. Two hour shame exposure (0 ppb ozone) will be conducted in a chamber after four weeks of supplementation

Sponsors & Collaborators

  • Fudan University

    lead OTHER

Principal Investigators

  • Haidong Kan, PhD · Department of Environmental Health, School of Public Health, Fudan University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-09-20
Primary Completion
2018-12-10
Completion
2019-12-30

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03697499 on ClinicalTrials.gov