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The Impact of Fish-oil Fatty Acids on Postprandial Vascular Reactivity

NCT01692431 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28

Last updated 2013-10-16

No results posted yet for this study

Summary

The primary aim of this study is to determine the impact of individual fish oil fatty acids on vascular reactivity and to identify underlying physiological and molecular mechanism of any observed effects. In addition response to intervention according to genotype will be determined retrospectively.

Conditions

  • Cardiovascular Physiological Phenomena
  • Endothelial Nitric Oxide Synthase
  • Eicosapentaenoic Acid
  • Docosahexaenoic Acid (All-Z Isomer)

Interventions

DIETARY_SUPPLEMENT

EPA

High fat meal containing EPA

DIETARY_SUPPLEMENT

DHA

High fat meal containing DHA

DIETARY_SUPPLEMENT

Placebo

High fat meal containing negligible EPA/DHA content

Sponsors & Collaborators

  • University of East Anglia

    lead OTHER

Principal Investigators

  • Anne Marie Minihane, PhD · University of East Anglia

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
35 Years
Max Age
55 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-09-30
Primary Completion
2013-10-31
Completion
2013-10-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01692431 on ClinicalTrials.gov