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Sex-related Differences in Sympathetic Vascular Transduction in the Setting of Hypoxemia

NCT05256069 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 31

Last updated 2025-09-15

No results posted yet for this study

Summary

The purpose of this project is to identify sex-related differences in the effect of hypoxia on sympathetic vascular transduction.

Conditions

Interventions

DRUG

Propranolol Pill

Participants will receive a β-blockade (propranolol pill, 1 mg/kg dosed based on participant weight).

DRUG

Placebo

Participants will receive a placebo in pill form.

Sponsors & Collaborators

Principal Investigators

  • Jacqueline K Limberg, Ph.D. · University of Missouri-Columbia

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-04-26
Primary Completion
2025-07-31
Completion
2025-07-31
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05256069 on ClinicalTrials.gov