Cardiol Therapeutics announced the publication of its Phase II MAvERIC study results in the Journal of the American Heart Association. The study showed CardiolRx led to rapid and sustained reductions in pericarditis pain and inflammation with a favorable safety profile. The findings support the ongoing Phase III MAVERIC trial.
AI is transforming cardiovascular medicine: $1.4B+ in investments, a new cardiac biomarker sensor, and stroke-imaging software in 2,500+ hospitals. FDA, EMA, and PMDA are opening clearer regulatory pathways.
Hematologic cancer survivors face elevated CVD risk and fourfold higher heart failure risk. Cardiac screening is low among cardiotoxic treatment recipients. A trial found simple risk assessment may suffice.
Multiple new studies highlight key factors affecting children's health and development. Research shows maternal cardiovascular health during pregnancy significantly impacts child developmental delays, with poor heart health increasing risk by 62%. A separate study found family finances and neighborhood opportunities account for about 16% of variability in children's brain function, while parental concern about illness proved highly accurate for detecting serious conditions in children.
Prothena reported Q4 and full year 2025 financial results with $308.4 million in cash as partners Roche and Novo Nordisk initiated Phase 3 trials for prasinezumab and coramitug, both expected to complete in 2029.
Three new CRISPR-based therapies show promise for treating heart failure through mitochondrial enhancement, cystic fibrosis via lipid nanoparticle gene insertion, and elevated cholesterol with single-dose gene editing targeting ANGPTL3.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07666048 |
Adapting Enhanced Supports to Improve Patient Adherence to Secondary Antibiotic Prophylaxis for Rheumatic Heart Disease |
NOT_YET_RECRUITING | |
| NCT07663292 |
Neuroplastic Changes Due to an Exercise Intervention That Aid in Lower Limb Recovery After Subcortical Stroke |
RECRUITING | NA |
| NCT07649616 |
Increasing Law Enforcement Application of Automated External Defibrillators (AED)s for Cardiac Arrest |
ENROLLING_BY_INVITATION | NA |
| NCT07635329 |
Home-based Vision Rehabilitation Guided by Brain Imaging |
RECRUITING | NA |
| NCT07634640 |
Hearts on Fire: Targeting Inflammation in Heart Failure With Preserved Ejection Fraction |
RECRUITING | EARLY_PHASE1 |
| NCT07599774 |
Optimal Targeted High-definition Transcranial Direct Current Stimulation for Reducing Post-stroke Upper Limb Motor Impairments |
NOT_YET_RECRUITING | NA |
| NCT07572175 |
Sotagliflozin as Prevention of Anthracycline-Related Cardiotoxicity |
NOT_YET_RECRUITING | PHASE2 |
| NCT07549477 |
A Study of Cardiac Magnetic Resonance Imaging (CMR) for Evaluating Catheter-Associated Right Atrial Clot in People With Cancer |
RECRUITING | NA |
| NCT07541118 |
Evaluating an Implementation Strategy to Improve Physical Activity and Reduce Cardiovascular Risk Factors in Children |
NOT_YET_RECRUITING | NA |
| NCT07518719 |
Feasibility of The Health Integrated Nutrition and Kidney Wellness Program |
RECRUITING | NA |
