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Physiologic Effect of Topical Nitroglycerin on Microcirculation Capacity in Patients With Circulatory Shock.

NCT05102734 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 44

Last updated 2024-04-01

Study results available
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Summary

This is an open-label, single center, trial that will enroll up to 25 participants with circulatory shock after cardiac surgery. Participants will be administered a topical sublingual nitroglycerin solution and assessed for changes microcirculatory blood flow using incident dark field microscopy.

Conditions

  • Circulatory Shock
  • Cardiovascular Shock

Interventions

DRUG

Nitroglycerin Topical Product

Topical nitroglycerin solution

Sponsors & Collaborators

Principal Investigators

  • John C. Greenwood, MD · University of Pennsylvania

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-09-01
Primary Completion
2022-02-01
Completion
2022-03-01
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05102734 on ClinicalTrials.gov