Conditioned Pharmacotherapeutic Effects in Hypertension
NCT02056626 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 44
Last updated 2019-07-09
Summary
The proposed research is designed to determine if the application of classical conditioning operations could influence the clinical effects of a regimen of antihypertensive drug therapy. It will be determined if, capitalizing on conditioned pharmacotherapeutic effects, patients can be effectively treated with smaller cumulative amounts of drug.
Conditions
Interventions
- DRUG
-
carvedilol
Sponsors & Collaborators
-
University of Rochester
lead OTHER
Principal Investigators
-
John D. Bisognano, M.D., Ph.D. · University of Rochester
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-03-31
- Primary Completion
- 2018-11-30
- Completion
- 2018-12-31
Countries
- United States
Study Locations
More Related Trials
-
Sex-related Differences in Sympathetic Vascular Transduction in the Setting of Hypoxemia
NCT05256069 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Does Statin Therapy Reduce Sympathoexcitation in Hypertension?
NCT00497016 ·Status: COMPLETED ·Phase: NA
-
Early Neurovascular Adaptations in Aging Women
NCT06520982 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Analysis of Atropine and Propranolol Induced Changes
NCT00251602 ·Status: COMPLETED ·Phase: PHASE1
-
A Study in Subjects With Neurogenic Orthostatic Hypotension
NCT07089043 ·Status: RECRUITING ·Phase: PHASE2
-
Effect of Beta-blockers on Structural Remodeling and Gene Expression in the Failing Human Heart
NCT01798992 ·Status: COMPLETED ·Phase: PHASE4
-
Clinical Outcome and Cost-effectiveness of Reduced Noradrenaline by Using a Lower Blood Pressure Target in Patients With Cardiogenic Shock From Acute Myocardial Infarction
NCT05168462 ·Status: RECRUITING ·Phase: PHASE4
-
Dosing Study of the Effects of Nebivolol on Blood Pressure in Black Patients With Mild to Moderate Hypertension
NCT00145236 ·Status: COMPLETED ·Phase: PHASE3
-
Phase II Study of Midodrine for Neurogenic Orthostatic Hypotension
NCT00004268 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of a Higher Blood-pressure on Right Ventricular Function
NCT03806582 ·Status: COMPLETED ·Phase: PHASE4
-
Caveolin-1 and Vascular Dysfunction
NCT01426529 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Phase Ⅲ Study of Extended-Release Carvedilol Sulfate for the Treatment of Hypertension
NCT01970059 ·Status: UNKNOWN ·Phase: PHASE3
-
Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients
NCT04620382 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Effect of Intrathecal Clonidine in Hypertensive Subjects With Poorly Controlled Blood Pressure
NCT01297335 ·Status: COMPLETED ·Phase: PHASE2
-
Nitrite Supplementation for Improving Physiological Function in Older Adults
NCT02393742 ·Status: COMPLETED ·Phase: NA
-
To Demonstrate the Relative Bioavailability of Atenolol Tablets
NCT00913965 ·Status: COMPLETED ·Phase: PHASE1
-
Tilt-Table Study of the Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension
NCT01518946 ·Status: COMPLETED ·Phase: PHASE4
-
Sympathetic Nervous System Modulation in Hypertension
NCT00491387 ·Status: TERMINATED ·Phase: PHASE4
-
Nebivolol in Patients With Systolic Stage 2 Hypertension
NCT01057251 ·Status: COMPLETED ·Phase: PHASE4
-
The Effects of Clonidine on the Diuretic Response in Cirrhotic Patients
NCT00356226 ·Status: COMPLETED ·Phase: NA
-
Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV
NCT02560805 ·Status: RECRUITING ·Phase: PHASE2
-
High Resolution Phenotyping in Healthy Humans
NCT00943774 ·Status: COMPLETED
-
Effects of the Beta-blocker Nebivolol (Bystolic) on Subjects With High Normal Blood Pressure and/or a Family History of Hypertension
NCT01202175 ·Status: COMPLETED ·Phase: PHASE4
-
Sympathetic Neurovascular Transduction: Role of Adrenergic Receptors and Sex Differences
NCT05997732 ·Status: RECRUITING ·Phase: PHASE4
-
Influence of the Autonomic Nervous System in Response to Exercise in Hypertensive Individuals
NCT04371757 ·Status: UNKNOWN ·Phase: NA