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Early Neurovascular Adaptations in Aging Women

NCT06520982 · Status: RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2025-11-26

No results posted yet for this study

Summary

Our goal is to enhance our understanding of early vascular adaptations in aging women with an emphasis on the sympathetic nervous system.

Conditions

  • Women
  • Sympathetic Nervous System
  • Aging
  • Blood Flow

Interventions

DRUG

Norepinephrine

Infused intra-arterially in a dose-response fashion

DRUG

Isoproterenol

Infused intra-arterially in a dose-response fashion

DRUG

Acetylcholine

Infused intra-arterially in a dose-response fashion

DRUG

Nitroprusside

Infused intra-arterially in a dose-response fashion

DRUG

Estrogen

Infused intra-arterially

Sponsors & Collaborators

  • American Heart Association (AHA)

    collaborator UNKNOWN

  • University of Missouri-Columbia

    lead OTHER

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-09-20
Primary Completion
2027-06-30
Completion
2028-06-30
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06520982 on ClinicalTrials.gov