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Comparison of the Genotoxicity of Desflurane and Propofol

NCT05185167 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2022-03-31

No results posted yet for this study

Summary

The purpose of this study is to evaluate if the anesthetics propofol and desflurane can damage DNA according to comet essay in patients submitted to lumbar disc surgery.

Conditions

  • DNA Damage
  • Anesthesia

Interventions

DRUG

Anesthetics, General Desflurane Maintenance

Comparison of dna damage of desflurane maintenance with propofol maintenance according to comet analysis

DRUG

Anesthetics, General Propofol Maintenance

Comparison of dna damage of propofol maintenance with desflurane maintenance according to comet analysis

Sponsors & Collaborators

  • Muğla Sıtkı Koçman University

    lead OTHER

Principal Investigators

  • Melike Korkmaz Toker, Assoc. Prof. · Mugla Sıtkı Kocman University Department of Anesthesiology and reanimation

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
DOUBLE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-01-17
Primary Completion
2022-03-15
Completion
2022-03-20

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05185167 on ClinicalTrials.gov