Acute Effects of Vaping Nicotine on Cognition in Young Adults
NCT04901208 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 8
Last updated 2024-03-22
Summary
To examine reward processing and cognitive control both with and without the influence of vaporized nicotine in young adults with no history of cigarette use using EEG and fMRI. The goal is to determine whether acute nicotine administration using a Juul device would impact functional correlates of reward and inhibitory control in people who commonly use juul devices.
Conditions
- Nicotine Addiction
- Vaping
Interventions
- DRUG
-
Nicotine pod
Nicotine pods administered to individuals who use Juul
- DRUG
-
Placebo pod
Nicotine-free pods administered to individuals who use Juul
Sponsors & Collaborators
-
National Center for Advancing Translational Sciences (NCATS)
collaborator NIH -
National Institute on Drug Abuse (NIDA)
collaborator NIH -
Yale University
lead OTHER
Principal Investigators
-
Kristen P Morie, PHD · Yale University
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 30 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-04-05
- Primary Completion
- 2022-08-17
- Completion
- 2022-08-17
Countries
- United States
Study Locations
More Related Trials
-
Effects of Electronic Cigarette Settings and Liquid Concentrations in Cigarette Smokers and Electronic Cigarette Users
NCT03710590 ·Status: COMPLETED ·Phase: NA
-
Mechanistic Evaluations of Pre-Cessation Therapies for Smoking Cessation
NCT01406223 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of Novel E-cigarette Constituents on Adults TCORS 3.0
NCT05932745 ·Status: RECRUITING ·Phase: NA
-
Effect of Different E-cigarette Cooling Flavors on Adults' Sensory Experience TCORS 3.0
NCT05932693 ·Status: COMPLETED ·Phase: NA
-
Trial on the Effect of E-cigarette Advertising on Cigarette Perceptions in Adolescents
NCT03786042 ·Status: COMPLETED ·Phase: NA
-
Reduced Nicotine Cigarette Purchasing Decisions
NCT04999644 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Acute and Chronic Nicotine Modulation of Reinforcement Learning
NCT01830842 ·Status: COMPLETED ·Phase: NA
-
The Effects of Menthol as Delivered by an Electronic Cigarette on the Desirability of Nicotine in Tobacco Users
NCT02102100 ·Status: COMPLETED ·Phase: NA
-
The Role of Nicotine and Non-Nicotine Alkaloids in E-Cigarette Use and Dependence
NCT02590393 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Adolescent Vaping Characterization and Parent Views on Adolescent Vaping Protocol
NCT05669716 ·Status: TERMINATED
-
IV Pulsed-Nicotine as a Model of Smoking: The Effects of Dose and Delivery Rate
NCT05176418 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Effects of E-Cigarette Flavors on Adults TCORS 2.0
NCT03635333 ·Status: COMPLETED ·Phase: PHASE1
-
Supplemental Nicotine Administration for Smoking Cessation in Posttraumatic Stress Disorder (PTSD)
NCT01055886 ·Status: COMPLETED ·Phase: NA
-
A Fmri Study on the Effects of a Conjugate Vaccine and Placebo on CNS Activation and Behavior Following a Nicotine Challenge
NCT01318668 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Effects of Smoking Environments on Brain Reactivity
NCT03421210 ·Status: COMPLETED ·Phase: PHASE4
-
Investigating Exposure to Toxicants From Smoking and Vaping
NCT05953220 ·Status: UNKNOWN
-
Improving the Efficacy of Anti-Nicotine Immunotherapy
NCT01280968 ·Status: COMPLETED ·Phase: PHASE2
-
Interactive Psychopharmacologic Effects of Alcohol and Nicotine in Humans
NCT00616746 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Varenicline and Nicotine Interactions in Humans (VA)
NCT00606892 ·Status: COMPLETED ·Phase: NA
-
Effects of Menthol in E-cigarettes on Smoking Behaviors
NCT04521647 ·Status: COMPLETED ·Phase: PHASE1
-
Does Sweet Taste Potentiate Nicotine Cue Reactivity?
NCT02499757 ·Status: COMPLETED ·Phase: PHASE1
-
Effects of Nicotine on Elements of Attentions in Smokers and Nonsmokers
NCT01034020 ·Status: COMPLETED ·Phase: PHASE1
-
Varenicline for Nicotine Vaping Cessation in Adolescents
NCT05367492 ·Status: COMPLETED ·Phase: PHASE4
-
A Safety and Cognitive Function Study of EVP-6124 Versus Placebo in Subjects With Nicotine Dependence
NCT01480232 ·Status: TERMINATED ·Phase: PHASE2
-
Evaluation of the Electronic Cigarette Withdrawal Syndrome
NCT06066996 ·Status: RECRUITING ·Phase: EARLY_PHASE1