Effects of E-Cigarette Flavors on Adults TCORS 2.0
NCT03635333 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 130
Last updated 2025-12-19
Summary
This study looks at the effects of flavors when administered with nicotine in e-cigarettes in younger and older adult cigarette smokers.
Conditions
- Nicotine Use Disorder
Interventions
- DRUG
-
Nicotine
Nicotine level (6 or 18 mg)
- DRUG
-
Flavor
Flavor of e-juice (tobacco, menthol, cherry, vanilla)
Sponsors & Collaborators
-
National Institute on Drug Abuse (NIDA)
collaborator NIH -
Yale University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 21 Years
- Max Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-05-14
- Primary Completion
- 2023-07-12
- Completion
- 2023-07-12
Countries
- United States
Study Locations
More Related Trials
-
Effect of Different E-cigarette Cooling Flavors on Adults' Sensory Experience TCORS 3.0
NCT05932693 ·Status: COMPLETED ·Phase: NA
-
Sensory Perception of Sweet Flavors in E-Cigarette
NCT03332953 ·Status: COMPLETED ·Phase: NA
-
Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1
NCT02179034 ·Status: COMPLETED ·Phase: PHASE1
-
The Effects of Menthol as Delivered by an Electronic Cigarette on the Desirability of Nicotine in Tobacco Users
NCT02102100 ·Status: COMPLETED ·Phase: NA
-
Oral Nicotine Pouch Marketing Features Influence on Perceptions
NCT06605924 ·Status: COMPLETED ·Phase: NA
-
Do Flavors Increase the Addiction Potential of Nicotine?
NCT04696380 ·Status: COMPLETED ·Phase: PHASE2
-
Nicotine Vapor Specific Sensory Measurement
NCT04533542 ·Status: COMPLETED
-
Effects of Novel E-cigarette Constituents on Adults TCORS 3.0
NCT05932745 ·Status: RECRUITING ·Phase: NA
-
Effects of Nicotine Pouch Characteristics on Perceptions and Behavior
NCT06597435 ·Status: RECRUITING ·Phase: NA
-
Effects of Menthol in E-cigarettes on Smoking Behaviors
NCT04521647 ·Status: COMPLETED ·Phase: PHASE1
-
Does Sweet Taste Potentiate Nicotine Cue Reactivity?
NCT02499757 ·Status: COMPLETED ·Phase: PHASE1
-
Nicotine Delivery Rate and Its Abuse Potential: Impact of Menthol
NCT03580525 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Evaluating E-Cigarette Nicotine Form, Concentration, and Flavors Among Youth
NCT05458895 ·Status: COMPLETED ·Phase: NA
-
E-cigarettes and Blood Vessel Function
NCT02740595 ·Status: COMPLETED ·Phase: NA
-
Consumer Assessment of Tobacco Flavor and Odor
NCT04358315 ·Status: TERMINATED
-
Menthol Flavored E-cigarette Use During a Simulated Ban of Menthol Cigarettes
NCT03164668 ·Status: COMPLETED ·Phase: NA
-
Effects of Electronic Cigarette Settings and Liquid Concentrations in Cigarette Smokers and Electronic Cigarette Users
NCT03710590 ·Status: COMPLETED ·Phase: NA
-
Testing the Effect of ENDS Flavors on Neurotransmission
NCT05836051 ·Status: COMPLETED ·Phase: NA
-
The Impact of Menthol Flavoring on Switching in Adult Menthol Smokers
NCT05555069 ·Status: RECRUITING ·Phase: NA
-
Nicotine's Potential Abuse With Menthol
NCT04535362 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Effects of Electronic Cigarettes on Nicotine Concentrations
NCT01775787 ·Status: COMPLETED ·Phase: NA
-
Acute Pharmacokinetic and Pharmacodynamic Effects of "Tobacco-Free" Oral Nicotine Pouches in Smokers
NCT05335915 ·Status: COMPLETED ·Phase: PHASE1
-
Reduced Nicotine Cigarette Purchasing Decisions
NCT04999644 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-cigarettes on Smoking Behavior
NCT06260683 ·Status: RECRUITING ·Phase: NA
-
Abuse Liability and Appeal of Oral Nicotine Products
NCT06506162 ·Status: RECRUITING ·Phase: NA