HIPWOODS - Health Effects Related to Exposure to Particle Pollution From Woodburning Stoves

NCT00673907 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2012-02-02

No results posted yet for this study

Summary

The study intends to focus on health effects and symptoms related to particle exposure from wood burning stoves

The objective is to determine whether moderate exposure to particles from wood smoke in a real life situation causes an systemic inflammatory response in peripheral blood or in lower airways. 24 healthy subjects (normal healthy subjects and mild asthmatics to study the asthmatic response) is selected for the study. A randomized double blind crossover procedure will be followed with a PM exposure concentration of 200ug/m3, 400ug/m3 or clean air as the control exposure. Exposure will take place in a climate chamber using wood burning in an appropriate wood stove.

Conditions

  • Airway Inflammation
  • Systemic Inflammation

Interventions

OTHER

Wood smoke particles

Subjects are exposed at rest to the exposures for 3 h in our climate chamber

Sponsors & Collaborators

  • University of Copenhagen

    collaborator OTHER
  • Aarhus University Hospital

    collaborator OTHER
  • University of Aarhus

    lead OTHER

Principal Investigators

  • Torben Sigsgaard, Professor · Department of Environmental and Occupational Medicine , Institute of Public Health , The Faculty of Health Sciences

Study Design

Allocation
RANDOMIZED
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
64 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-01-31
Primary Completion
2008-06-30
Completion
2009-11-30

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00673907 on ClinicalTrials.gov