HIPWOODS - Health Effects Related to Exposure to Particle Pollution From Woodburning Stoves
NCT00673907 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2012-02-02
Summary
The study intends to focus on health effects and symptoms related to particle exposure from wood burning stoves
The objective is to determine whether moderate exposure to particles from wood smoke in a real life situation causes an systemic inflammatory response in peripheral blood or in lower airways. 24 healthy subjects (normal healthy subjects and mild asthmatics to study the asthmatic response) is selected for the study. A randomized double blind crossover procedure will be followed with a PM exposure concentration of 200ug/m3, 400ug/m3 or clean air as the control exposure. Exposure will take place in a climate chamber using wood burning in an appropriate wood stove.
Conditions
- Airway Inflammation
- Systemic Inflammation
Interventions
- OTHER
-
Wood smoke particles
Subjects are exposed at rest to the exposures for 3 h in our climate chamber
Sponsors & Collaborators
-
University of Copenhagen
collaborator OTHER -
Aarhus University Hospital
collaborator OTHER -
University of Aarhus
lead OTHER
Principal Investigators
-
Torben Sigsgaard, Professor · Department of Environmental and Occupational Medicine , Institute of Public Health , The Faculty of Health Sciences
Study Design
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 64 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2007-01-31
- Primary Completion
- 2008-06-30
- Completion
- 2009-11-30
Countries
- Denmark
Study Locations
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