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Effects of Low Dose Ozone on Airway Inflammatory Responses in Adults With Asthma - Sedentary Nasal Ozone (Asthma SNOZ)

NCT04109807 · Status: SUSPENDED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 18

Last updated 2025-12-17

No results posted yet for this study

Summary

To determine if low levels of ozone (O3) encountered on a typical day in Chapel Hill will decrease spirometric values in mild asthmatics.

Conditions

  • Asthma, Allergic

Interventions

OTHER

Ozone

ozone exposure

OTHER

FA

Filtered air exposure

Sponsors & Collaborators

  • Environmental Protection Agency (EPA)

    collaborator FED

  • North Carolina State University

    collaborator OTHER

  • University of North Carolina, Chapel Hill

    lead OTHER

Principal Investigators

  • David Peden, MD · UNC SOM

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-12-16
Primary Completion
2027-08-31
Completion
2027-08-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04109807 on ClinicalTrials.gov