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Recruitment Assessment in Patients With Acute Respiratory Distress Syndrome and Covid-19

NCT05248243 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 41

Last updated 2023-11-13

No results posted yet for this study

Summary

Respiratory failure associated with Covid-19 can be expressed as acute respiratory distress syndrome (ARDS), which is an acute inflammatory lung injury,which generally requires the use of invasive mechanical ventilation (MV). There are inconclusive results regarding the potential lung recruitment in ARDS.

At the lung level, the relationship between lung volume and pressure can be graphed through a pressure/volume (P/V) curve. In this curve, hysteresis (H) can be evaluated, which is the amount of energy generated during inspiration that is not recovered during expiration. H is related to recruitment, assuming that the greater H the greater the alveolar recruitment. For this reason, the objective of this study is the measurement of H as a way to assess the lung recruitment capacity, in patients with ARDS and in patients with Covid-19 who develop ARDS (ARDS- Covid)

Conditions

Interventions

PROCEDURE

Recruitment assessment

Intervention Details: Construction of the P/V curve with subsequent measurement of HR and Vmax.

Sponsors & Collaborators

  • Ramos Mejía Hospital

    lead OTHER

Eligibility

Min Age
15 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-03-07
Primary Completion
2023-03-07
Completion
2025-03-01

Countries

  • Argentina

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05248243 on ClinicalTrials.gov