MedTrace Logo

Changes in Lung Aeration and Inspiratory Effort With and Without Awake Prone

NCT05719103 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2023-05-09

No results posted yet for this study

Summary

The investigators aimed to investigate the ventilation homogeneity and transpulmonary pressure during treatments of High-flow nasal cannula(HFNC) and (CPAP) on supine and prone position for COVID-19 or non-COVID-19 patients with acute hypoxemic respiratory failure (AHRF).

Conditions

  • Respiratory Distress Syndrome
  • Ventilation Therapy; Complications

Interventions

BEHAVIORAL

With and Without Awake Prone Positioning

1. HFNC flow at 60 L/min or maximum tolerable flow at supine position 2. HFNC flow at 60 L/min or maximum tolerable flow at prone position 3. CPAP with full face mask at 10 cmH2O at supine position 4. CPAP with full face mask at 10 cmH2O at prone position 5. MC at supine position 6. MC at prone position

Sponsors & Collaborators

  • Shanghai Zhongshan Hospital

    lead OTHER

Principal Investigators

  • Ming Zhong, MD, phD · Fudan University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-09
Primary Completion
2023-12-31
Completion
2025-12-31

Countries

  • China

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05719103 on ClinicalTrials.gov