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Anabolic Potential of 3-hydroxybutyrate (3-OHB) and Whey Protein in a Human Catabolic Inflammatory Disease Model

NCT04064268 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 8

Last updated 2020-06-11

No results posted yet for this study

Summary

This study aims to investigate the muscle anabolic potential of adding ketone (3-hydroxybutyrate) to whey protein compared with isocaloric, isonitrogenous whey protein in a human model of inflammatory catabolic disease. Further, this study aims to investigate whether the same amount of whey protein has different effects on muscles in an catabolic inflammatory setting compared with a healthy setting.

Conditions

  • Endotoxemia
  • Muscle Loss
  • Catabolic State
  • Protein; Disease
  • Nutrition Therapy

Interventions

DIETARY_SUPPLEMENT

Whey

45 g whey + 20 g maltodextrin

DIETARY_SUPPLEMENT

3-OHB + Whey

50 g ketone + 45 g whey + 20 g maltodextrin

Sponsors & Collaborators

  • Arla Foods Ingredients

    collaborator UNKNOWN

  • Aarhus University Hospital

    collaborator OTHER

  • University of Aarhus

    lead OTHER

Principal Investigators

  • Niels Moeller, Professor · Aarhus University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
40 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-06-17
Primary Completion
2020-01-23
Completion
2020-01-23

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04064268 on ClinicalTrials.gov