Mechanisms of Inflammation, Immunity, Islet Cell and Intestinal Hormone Changes in Youth at Risk for Diabetes
NCT04031222 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 52
Last updated 2022-09-13
Summary
This study intends to assess the role of inflammation in insulin resistant conditions (i.e., obesity and pre-diabetes) and the subsequent development of disease, such as type 2 diabetes (T2D) and cardiovascular disease (CVD), in the adolescent population.
Conditions
- Obesity
- PreDiabetes
- Adolescent Obesity
- Inflammation
- Metabolic Problems
- Insulin Resistance
- Gut Microbiome
- Immunity
- Beta Cell Dysfunction
- Gut Hormones
Sponsors & Collaborators
-
University of Toronto
collaborator OTHER -
University of Guelph
collaborator OTHER -
Sunnybrook Health Sciences Centre
collaborator OTHER -
The Hospital for Sick Children
lead OTHER
Principal Investigators
-
Jill K Hamilton, MD · The Hospital for Sick Children
Eligibility
- Min Age
- 12 Years
- Max Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-05-19
- Primary Completion
- 2019-02-15
- Completion
- 2019-03-01
Countries
- Canada
Study Locations
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