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Nitrite Effects on Cardiac Muscle in CABG

NCT04001283 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 75

Last updated 2019-06-28

No results posted yet for this study

Summary

The purpose of this study is to test whether sodium nitrite affects the expression of cellular proteins important for metabolic and vascular function in vascular offcuts and cardiac biopsies taken from patients undergoing coronary artery bypass grafting (CABG) surgery.

Conditions

Interventions

DRUG

Sodium Nitrite

Intravenous drug infusion

DRUG

0.9% Sodium-chloride

Matched placebo

Sponsors & Collaborators

  • University of East Anglia

    lead OTHER

Principal Investigators

  • Michael P Frenneaux, MD, FRCP · Clinical Professor, Norwich Medical School, The University of East Anglia, UK

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-01-21
Primary Completion
2019-07-01
Completion
2019-07-01

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04001283 on ClinicalTrials.gov