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Coronary Artery Bypass and Nitrate Oral Supplementation

NCT01348971 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2013-09-26

No results posted yet for this study

Summary

The purpose of this study is to determine whether oral sodium nitrate administration prior to coronary artery bypass surgery can reduce perioperative levels of troponin T. In addition, plasma and urine surrogate markers of renal, hepatic and brain injury will be monitored.

Conditions

Interventions

DIETARY_SUPPLEMENT

Sodium nitrate

Preoperative oral administration of sodium nitrate. 700 mg the night before surgery and 700 mg three hours before surgery

OTHER

Sodium chloride

Preoperative oral administration of sodium chloride the night before surgery and three hours before surgery

Sponsors & Collaborators

Principal Investigators

  • Eddie T Weitzberg, MD,PhD · Karolinska Institutet

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-03-31
Primary Completion
2013-02-28
Completion
2013-02-28

Countries

  • Sweden

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01348971 on ClinicalTrials.gov