Diabetes mellitus is a chronic metabolic disease characterized by elevated blood glucose due to defects in insulin secretion, insulin action, or both. Major forms include type 1 and type 2 diabetes.
New research shows posture-driven retinal vascular changes can predict diabetic retinopathy progression, with smartphone-based imaging detecting early microvascular dysfunction. A five-year study found abnormal arteriolar tortuosity during postural shifts increased progression risk over two-fold.
Acromegaly patients face persistent symptoms including fatigue, joint pain, headaches, and brain fog despite biochemical control. Treatment burden and financial barriers remain significant, particularly in sub-Saharan Africa where diagnostic tools and therapies are often inaccessible.
Experimental topical therapies for diabetic foot ulcers are showing early promise. Studies described probiotic-based treatments, a medieval antimicrobial mixture and a quercetin-loaded hyaluosome gel with anti-inflammatory and wound-healing effects.
A 30-year-old female with stage IV gallbladder adenocarcinoma achieved complete metabolic resolution of metastases after three cycles of pembrolizumab, gemcitabine, and cisplatin, despite presenting without traditional risk factors.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07614659 |
Uppsala Self-Screening of Cardiovascular Health (U-SCREEN) |
RECRUITING | NA |
| NCT07591415 |
Validation of an App in the Elderly Population With Diabetes Mellitus. |
COMPLETED | NA |
| NCT07581262 |
Risk Perception Intervention for High-Risk Diabetic Foot |
NOT_YET_RECRUITING | NA |
| NCT07560059 |
Acute Metabolic Outcomes in Diabetic Patients Hospitalized for COVID-19 (DMD-COV) |
COMPLETED | |
| NCT07552571 |
Goal Commitment and Proactive Health Behavior in Chronic Disease Patients |
RECRUITING | NA |
| NCT07548372 |
SPARK-CGM Implementation |
NOT_YET_RECRUITING | NA |
| NCT07543211 |
Effectiveness of Laser Acupuncture in Improving Arterial Stiffness Among Patients With Cardiorenal Metabolic Syndrome |
NOT_YET_RECRUITING | |
| NCT07540754 |
A Study to Evaluate the Pharmacokinetics of HRS9531 Injection in Participants With Mild, Moderate, and Normal Hepatic Function |
RECRUITING | PHASE1 |
| NCT07538466 |
A Study to Evaluate the Safety and Pharmacokinetics of AD-123 Compared to Coadministration of AD-1231 and AD-1232 |
NOT_YET_RECRUITING | PHASE1 |
| NCT07536516 |
Measurement of Ocular Blood Flow and Retinal Oxygen Extraction in Diabetic Patients |
RECRUITING | NA |
