Diabetes mellitus is a chronic metabolic disease characterized by elevated blood glucose due to defects in insulin secretion, insulin action, or both. Major forms include type 1 and type 2 diabetes.
New research shows posture-driven retinal vascular changes can predict diabetic retinopathy progression, with smartphone-based imaging detecting early microvascular dysfunction. A five-year study found abnormal arteriolar tortuosity during postural shifts increased progression risk over two-fold.
Trial: VPM1002/Immuvac show limited overall TB protection but up to 50.4% efficacy vs extrapulmonary TB. Modeling: blocking asymptomatic TB key to long-term vaccine impact. Also: STEP-TB safety study and CDC Asia funding.
Acromegaly patients face persistent symptoms including fatigue, joint pain, headaches, and brain fog despite biochemical control. Treatment burden and financial barriers remain significant, particularly in sub-Saharan Africa where diagnostic tools and therapies are often inaccessible.
New research shows AI can predict heart disease risk from breast arterial calcification on mammograms, while the BRAIx tool helps assess breast cancer risk. A $16 million U.S. trial, PRISM, will evaluate AI-assisted reading of screening mammograms.
Experimental topical therapies for diabetic foot ulcers are showing early promise. Studies described probiotic-based treatments, a medieval antimicrobial mixture and a quercetin-loaded hyaluosome gel with anti-inflammatory and wound-healing effects.
A 30-year-old female with stage IV gallbladder adenocarcinoma achieved complete metabolic resolution of metastases after three cycles of pembrolizumab, gemcitabine, and cisplatin, despite presenting without traditional risk factors.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07779044 |
Mindfulness-Based Cognitive Behavioral Program for People With Diabetes Mellitus |
COMPLETED | NA |
| NCT07776535 |
Effects Of Otago Exercise Versus Multisensory Integration Training On Balance And Gait In Elderly With Diabetes |
NOT_YET_RECRUITING | NA |
| NCT07753681 |
Domestication and Implementation of the PEN-Plus Clinical Model in the Zambian Health System |
RECRUITING | |
| NCT07747675 |
Cognitive Intervention for Cognitive Impairment |
NOT_YET_RECRUITING | NA |
| NCT07745998 |
The BRIGHT Study (Device Name: HALO System) |
NOT_YET_RECRUITING | NA |
| NCT07728162 |
Cold Spray for Insulin-Injection Pain in the Emergency Department |
COMPLETED | NA |
| NCT07707778 |
Tirzepatide's Effects on Epigenetic Aging and Metabolic Restoration in Virally Suppressed People With HIV |
ENROLLING_BY_INVITATION | PHASE4 |
| NCT07705958 |
OTAGO Exercises in Diabetes Mellitus Examining Its Effectiveness |
NOT_YET_RECRUITING | NA |
| NCT07696910 |
Perioperative Hypoglycemia in Diabetic Patients Undergoing Vitrectomy: a Masked CGM Prospective Observational Study |
NOT_YET_RECRUITING | |
| NCT07665775 |
Effectiveness of an Inpatient Rehabilitation and Prosthetic Training Model in Patients With Vascular and Metabolic Transfemoral Amputation |
NOT_YET_RECRUITING |
