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Investigation of Myocardial Protection Level With Specific Cardioplegia Methods in Cardiac Surgery

NCT05603429 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 74

Last updated 2023-08-14

No results posted yet for this study

Summary

Investigating the myocardial effects of cold blood cardioplegia and del nido cardioplegia solution, which are routinely used in clinical practice, will contribute to the studies in the literature on the safety and efficacy of these two methods.

For this purpose, patients with coronary artery disease that going to be Coronary Artery Bypass Graft (CABG) surgery will be classified within the scope of the SYNTAX score, the level of exposure to cardioplegia change in proportion to their score will be examined. Also, left ventricular muscle mass will be calculated in patients who will undergo Aortic Valve replacement (AVR) due to Aortic Stenosis, and myocardial protection level proportional to muscle mass will be examined, and cardioplegia efficiency will be compared.

Conditions

  • Bypass Complication
  • Cardioplegia Solution Adverse Reaction
  • Endothelial Degeneration
  • Oxidative Stress
  • Aortic Valve Stenosis
  • Coronary Artery Disease

Interventions

DIAGNOSTIC_TEST

Endocan, E-Selectin, TNF-alpha, Total Oxidant and Antioxidant Status

Endocan, E-Selectin, TNF-alpha, Total Oxidant and Antioxidant Status measurements for determining Endothelial Damage and Oxidative Stress

Sponsors & Collaborators

  • Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital

    lead OTHER

Principal Investigators

  • Bulend KETENCI · Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-10-13
Primary Completion
2023-07-25
Completion
2023-08-08

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05603429 on ClinicalTrials.gov