Post Coronary Artery Bypass Graft (CABG) Study
NCT00000463 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL
Last updated 2016-04-14
Summary
To determine the relative effectiveness of moderate versus more aggressive lipid lowering, and of low dose anticoagulation versus placebo, in delaying saphenous vein coronary bypass graft atherosclerosis and preventing occlusion of saphenous grafts of patients with saphenous vein coronary bypass grafts placed 1 to 11 years previously.
Conditions
- Cardiovascular Diseases
- Coronary Disease
- Heart Diseases
- Myocardial Ischemia
Interventions
- DRUG
-
lovastatin
- DRUG
-
cholestyramine
- DRUG
-
warfarin
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
lead NIH
Principal Investigators
-
Genell Knatterud · Maryland Medical Research Institute
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1987-04-30
- Completion
- 1998-12-31
More Related Trials
-
Improving Outcomes and Quality of Life After CABG
NCT00005690 ·Status: COMPLETED
-
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
NCT04045665 ·Status: RECRUITING ·Phase: PHASE3
-
The Effect Of Acadesine On Reducing Cardiovascular and Cerebrovascular Adverse Events In Coronary Artery Bypass Graft (CABG) Surgery (Study P05633 AM1)(TERMINATED)
NCT00872001 ·Status: TERMINATED ·Phase: PHASE3
-
Fibrinogen and Bleeding After Cardiac Surgery
NCT00968045 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of RO4905417 in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery
NCT01245634 ·Status: COMPLETED ·Phase: PHASE2
-
Study of INS50589 Intravenous Infusion in Subjects Undergoing Coronary Artery Bypass Grafting (CABG) Involving Cardiopulmonary Bypass
NCT00316212 ·Status: TERMINATED ·Phase: PHASE2
-
Total Arterial vs. Mixed Grafting in Left Coronary CABG
NCT07057713 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Remote Ischemic Conditioning and Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG)
NCT01107184 ·Status: TERMINATED ·Phase: NA
-
A Safety and Efficacy Study to Confirm the Cardioprotective Effects of MC-1 in Patients Undergoing High-Risk CABG
NCT00402506 ·Status: COMPLETED ·Phase: PHASE3
-
Saphenous Vein Allografts for Coronary Bypass
NCT01386021 ·Status: COMPLETED
-
Prior CABG Patients Evaluated for Saphenous VeIn grAft DysfUnction and Progression of Coronary arTery Disease
NCT04772768 ·Status: RECRUITING
-
Improving the Results of Heart Bypass Surgery Using New Approaches to Surgery and Medication
NCT01047449 ·Status: COMPLETED ·Phase: NA
-
Study Of Factors Favoring The Onset Of Novo Atrial Fibrillation In The Immediate Aftermath Of Coronary Artery Bypass Surgery
NCT02042547 ·Status: COMPLETED
-
Effect of Evolocumab on Saphenous Vein Graft Patency Following Coronary Artery Bypass Surgery
NCT03900026 ·Status: COMPLETED ·Phase: PHASE4
-
Colchicine in Coronary Artery Bypass Graft (CABG)
NCT02122484 ·Status: COMPLETED ·Phase: PHASE4
-
Coronary Artery Bypass Grafting: Factors Related to Late Events and Saphenous Graft Patency
NCT00755248 ·Status: UNKNOWN
-
Ticagrelor-based De-escalation of Dual Antiplatelet Therapy After Coronary Artery Bypass Grafting
NCT05380063 ·Status: COMPLETED ·Phase: PHASE4
-
The Epidemiology of Bleeding and Clotting in Patients Undergoing Heart Transplantation, Coronary Artery Bypass Graft Surgery,or Implantation of Left Ventricular Assist Devices
NCT01481012 ·Status: TERMINATED
-
Prevention of Post-OP AFib Using Combination of CardiaMend and Amiodarone
NCT05681182 ·Status: COMPLETED ·Phase: PHASE4
-
ThrombElastoGraphic Haemostatic Status and Antiplatelet Therapy After Coronary Artery Bypass Graft Surgery
NCT01046942 ·Status: UNKNOWN ·Phase: PHASE3
-
Antithrombotic Therapy After Coronary Artery Bypass Grafting Combined With Coronary Endarterectomy
NCT05782270 ·Status: RECRUITING ·Phase: PHASE4
-
Randomized Endo-Vein Graft Prospective
NCT01850082 ·Status: COMPLETED ·Phase: NA
-
A Study of Anginera In Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery
NCT00364390 ·Status: UNKNOWN ·Phase: PHASE1
-
DACAB Trial: Follow-up Extension
NCT03987373 ·Status: COMPLETED
-
Systematic Assessment of Competitive Flow in Coronary Artery Bypass Grafts by Wave Intensity Analysis
NCT01118468 ·Status: UNKNOWN