MedTrace Logo

Biomarkers for Circadian Timing in Healthy Adults

NCT03956745 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2025-08-03

No results posted yet for this study

Summary

Study investigators want to learn more about the underlying biological clock and to see if the timing of that clock can be estimated from a single blood sample.

Conditions

  • Sleep Wake Disorders
  • Sleep Disorders, Circadian Rhythm
  • Sleep Disorders, Intrinsic
  • Advanced Sleep Phase Syndrome (ASPS)
  • Advanced Sleep Phase Syndrome
  • Advanced Sleep Phase
  • Delayed Sleep Phase
  • Delayed Sleep Phase Syndrome
  • Non-24 Hour Sleep-Wake Disorder
  • Irregular Sleep-Wake Syndrome
  • Shift-Work Sleep Disorder
  • Shift Work Type Circadian Rhythm Sleep Disorder
  • Delayed Phase Sleep Syndrome

Interventions

BEHAVIORAL

sleep-wake timing

Study participants will have one inverted day when they are scheduled to sleep \~12h opposite their usual sleep time.

BEHAVIORAL

constant routine

Study participants will spend \~28-50 hours awake, inactive, sitting in bed, in constant lighting and temperature.

Sponsors & Collaborators

  • Stanford University

    collaborator OTHER

  • Charite University, Berlin, Germany

    collaborator OTHER

  • Brigham and Women's Hospital

    lead OTHER

Principal Investigators

  • Jeanne F Duffy, MBA, PhD · Brigham and Women's Hospital

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-06-01
Primary Completion
2023-12-31
Completion
2025-04-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03956745 on ClinicalTrials.gov