Sleep and Circadian Mechanisms of Non-dipping Blood Pressure
NCT03558893 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2025-05-15
Summary
This study will be the first to distinguish the relative contributions of sleep, circadian and behavioral mechanisms to the non-dipping BP profile in Black adults and will lay the groundwork for optimizing therapies dependent on mechanisms, such as targeting sleep, targeting circadian rhythmicity, or targeting behaviors, and raising the possibility that ideal therapy for hypertension (HTN) may differ by race. This research will ultimately help to improve health and survival in black populations with HTN.
Conditions
- Hypertension
- Cardiovascular Risk Factor
Interventions
- BEHAVIORAL
-
Forced Desynchrony
All sleep opportunities and other activities will be scheduled by the experimenter so that by the end of the study these activities are spread evenly across all phases of the internal body clock.
Sponsors & Collaborators
-
Oregon Health and Science University
lead OTHER
Principal Investigators
-
Steven A Shea, PhD · Ore
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 40 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-12-01
- Primary Completion
- 2024-12-31
- Completion
- 2024-12-31
Countries
- United States
Study Locations
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