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Impact of Inulin on Production of Phenolic Acids From Tomato Onion and Lovage Soup

NCT03577145 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2019-01-18

No results posted yet for this study

Summary

This is an acute human bioavailability study in self-reported healthy participants aged 20-70 years old. The investigators hypothesize that combination of polyphenolics from a soup rich in rutin and quercitin and the non-digestible carbohydrate (NDC) inulin will increase the production of phenolic acids by bacteria in the human colon and these will be detected in urine. Participants will attend for three arms in a randomized order: Tomato, onion and lovage soup (high polyphenol food), Inulin (NDC) or Mixture of tomato, onion and lovage soup and inulin.

During each feeding study, urine, blood and stool samples will be collected at regular intervals for the duration of 24 hrs after consumption of test food. Participants will be asked to follow a low polyphenol diet for 2 days prior to the feeding study.

Conditions

  • Healthy Adults

Interventions

DIETARY_SUPPLEMENT

Tomato, onion & lovage soup with inulin

Source of polyphenols and non digestible carbohydrate

DIETARY_SUPPLEMENT

Tomato, onion & lovage soup

Source of polyphenols

DIETARY_SUPPLEMENT

Inulin

Source of non digestible carbohydrate

Sponsors & Collaborators

  • Scottish Universities Environmental Research Centre

    collaborator OTHER

  • University of Glasgow

    lead OTHER

Principal Investigators

  • Christine Edwards, PhD · University of Glasgow

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-07-27
Primary Completion
2018-12-31
Completion
2018-12-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03577145 on ClinicalTrials.gov