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Mechanisms of Alcohol Sensitivity in AERD

NCT03441438 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2018-05-07

No results posted yet for this study

Summary

The purpose of this study is to determine what type of reactions in the body may be responsible for the respiratory symptoms that occur when patients with Aspirin Exacerbated Respiratory Disease (AERD) drink alcoholic beverages. These reactions are most often seen with red wine.

Conditions

  • Aspirin-Sensitive Asthma With Nasal Polyps
  • Samter's Syndrome

Interventions

DIETARY_SUPPLEMENT

Water

Serum and urine markers will be obtained after drinking 5 oz of water

DIETARY_SUPPLEMENT

Red wine

Serum and urine markers will be obtained after drinking 5 oz of water

DIETARY_SUPPLEMENT

Polyphenolic Compounds

Serum and urine markers will be obtained after consuming 100 mg of provinols powder

Sponsors & Collaborators

  • University of Virginia

    lead OTHER

Principal Investigators

  • Spencer C Payne, MD · University of Virginia

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
21 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-05-01
Primary Completion
2018-09-01
Completion
2018-09-01

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03441438 on ClinicalTrials.gov